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Psycho- Oncology Journal (Jurnal Vol 28 no 4 2019
Abstract
Objective
Healthâ€related quality of life (HRQoL), psychosocial distress, and unmet health needs are important patientâ€reported outcomes (PROs) for patients with sarcoma treated with curative intent. Syntheses of data on these PROs in patients with sarcoma are limited.
Methods
A systematic review of peerâ€reviewed literature published between 2007 and 2017 was conducted using five databases, guided by the PRISMA and Cochrane reporting guidelines.
Results
Of 7240 articles identified, 31 were included in this review. Compared with healthy individuals, patients with sarcoma frequently scored lower in physical and psychological HRQoL domains and experienced higher rates of selfâ€image issues, depression, and suicide. However, outcomes for patients with sarcoma were relatively comparable to those with other malignancies. Anxiety symptoms were more common in the diagnosis phase, while depressive symptoms were more common in the treatment phase. Patients who are older, female, and socially isolated often reported lower HRQoL. As a sarcomaâ€specific HRQoL instrument is not available, and all studies have used generic instruments, key issues may have been omitted.
Conclusion
There are few studies reporting data for HRQoL, psychosocial issues, or unmet health needs in this population. A sarcomaâ€specific HRQoL instrument is needed to accurately describe outcomes in this population. There is a need for further qualitative research to conceptualise the HRQoL issues relevant to this population, against which to map existing HRQoL instruments and guide adaptation or creation of a new instrument.
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